JACKSON, Wyo. \u2014 A multi-vehicle wreck on Interstate 80 between Laramie and Cheyenne has closed that stretch of highway yet again this season. Wyoming Department of Transportation and Wyoming Highway Patrol are cleaning up the scene and finishing their investigation. The accident occurred late this morning near milemarker 331 on I-80. Interstate 80 is currently closed both directions between Cheyenne and Laramie. It is not known how long the interstate will be closed.